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Leriglitazone halts disease progression in adult patients with early cerebral adrenoleukodystrophyBrain
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Safety and efficacy of leriglitazone for preventing disease progression in men with adrenomyeloneuropathy (ADVANCE): a randomised, double-blind, multi-centre, placebo-controlled phase 2–3 trialLancet Neurology
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Clinical pharmacokinetics of leriglitazone and a translational approach using PBPK modeling to guide the selection of the starting dose in childrenCPT: Pharmacometrics & Systems Pharmacology
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The brain penetrant PPAR GAMMA agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophyScience Translational Medicine
2021
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