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    The NEXUS Clinical Study in cALD
    Home Clinical Studies NEXUS
  • The NEXUS Clinical Study in cALD

    The NEXUS trial is a phase 2/3, open-label clinical study that has been designed to assess the efficacy and safety of leriglitazone in pediatric patients with early stage cerebral adrenoleukodystrophy (cALD). This study is part of the Pediatric Investigational Plan (PIP) approved by EMA for leriglitazone in X-ALD.

    The NEXUS study is recruiting cALD patients with first evidence of cerebral MRI lesions. All patients will be receiving leriglitazone and they will be carefully monitored for safety, changes in clinical symptoms and in cerebral MRI lesions. The study has been designed with input from both EMA and FDA, and EU and US clinical experts in X-ALD and patient advocacy groups. The study design does not interfere with the current Standard of Care and does not delay haematopoietic stem cell transplantation if it becomes indicated.

    For further information visit:
    https://www.clinicaltrialsregister.eu/ctr-search/search?query=2019-000654-59

    Hospitals involved in NEXUS Clinical Study
    See map
    ICM, Groupe Hospitalier Pitié Salpêtrière
    Paris
    France
    University Medical Center Hamburg-Eppendorf
    Hamburg
    Germany
    Klinik für Kinder- und Jugendmedizin
    Göttingen
    Germany
    Hospital Sant Joan de Déu
    Barcelona
    Spain
    Hospitals involved in NEXUS Clinical Study
    See list
    Map
    ICM, Groupe Hospitalier Pitié Salpêtrière
    Paris
    France
    University Medical Center Hamburg-Eppendorf
    Hamburg
    Germany
    Klinik für Kinder- und Jugendmedizin
    Göttingen
    Germany
    Hospital Sant Joan de Déu
    Barcelona
    Spain
  • Contact

    Feel free to contact us in case you are interested in any of these clinical studies

    info@minoryx.com
    +34 93 544 14 66
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